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Thanksgiving Turkey should ideally be thawed whilst still in its original plastic wrapper. Defrosting turkey at room temperature is an absolute no-no. Bacteria breed and multiply very rapidly at room temperature turning your turkey into a potential bacteria-magnet. Instead, place your still-wrapped turkey in the rear of the refrigerator, which is the coldest part. Always place a large enough tray under the turkey to catch the melted ice and juices that are likely to leak.